[PUBLICATION] Cervical Cancer Screening in France
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Prevalence of high-risk cervical HPV infections in France: what is the difference between opportunistic screening and organized screening?

Our biologists Mathilde Roussel (Cerba Laboratory) and Stéphanie Haim-Boukobza (Cerba HealthCare) are contributing to a major national study published in Eurosurveillance (2025).

 

 

Methods

 

The study analyzes 362,963 HPV tests performed between 2020 and 2023 through a large network of medical biology laboratories.

Advanced statistical modeling makes it possible to map the prevalence of HPV16/18 infections and 12 other oncogenic genotypes at the postal code level.

 

 

Key Results
 

  • 3.7% of tests are positive for HPV16/18 and 9.2% for other genotypes.

     

  • Rates are higher in opportunistic screening (3.8% and 9.4%) than in organized screening (2.9% and 6.9%).

     

  • A geographical heterogeneity is observed, with a northwest/southeast gradient and “hotspots” along the Italian, Spanish, and Swiss borders.

 

 

Public Health Implications


Opportunistic screening overestimates the true prevalence of high-risk HPV.
Organized screening provides a more representative picture, which is key to tailoring prevention, screening, and vaccination strategies.

 

 

Reference : Supplisson O. et al., Eurosurveillance 2025

 

🔗To learn more: Read the article

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